veda active centella asiatica
Composition and molecular structure
The main active of Centella asiatica are triterpenic saponins. The main saponins are asiaticoside and madecassoside that range from 1 to 8%, as well as tannins, vegetable oils, phytosterols, ...
According to the Royal Spanish Pharmacopoeia, Centella asiatica must contain not less than 6% of total triterpenic derivatives expressed as asiaticoside, and calculated from the dried drug.
Mechanism of action
Centella asiatica acts on fibroblasts connective tissue, both in the vascular walls and around the vessel, modulating the synthesis of collagen.
It increases the tensile strength of the skin promoting a healing action.
It inhibits the inflammatory process that could lead to hypertrophy in scars and improves capillary permeability.
It inhibits keratinocytes proliferation.
Several studies show re-epithelializating and healing actions of Centella asiatica in oral and topical administration of the extract in a wound in skin’s rat.
The results showed that Centella asiatica intervenes in wound repair phases.
Applying Centella asiatica is based on its regenerative capacity. It has different applications:
Healing: Improves wounds and burns healing through in vitro stimulation of collagen production, key protein in wound healing. Moreover, it stimulates fibroblasts activation, thus has a re-epithelizating action.
Psoriasis and as a preventive in the formation of keloid scars by inhibiting the keratinocytes proliferation.
Inci name: Centella asiatica extract
Purity: Asian 34.0% to 44.0% / Genin 54.0% to 66.0%
Dosage: 0.1 to 0.5%